Tom is the latest member to join the Rab Group, here is what he has to say:
“I am a doctor training in neurology and have joined the group to undertake my PhD. We aim to convert cells taken from skin samples directly into nerve cells (induced neurons). This will allow us to look into the underlying mechanisms that are going wrong in these cells, to provide insight into why people develop Parkinson’s disease. Specifically we will be looking at cells taken from patients with mutations in the gene called GBA1 which is the commonest mutation seen in Parkinson’s disease, focusing on problems with the autophagy-lysosomal pathways. This model will eventually allow for testing of potential new Parkinson’s disease treatments on nerve cells”.